Breastfeeding

DRUG SAFETY ALERT: Drugs Contraindicated in Breastfeeding

  Drugs that are contraindicated in breastfeeding  Amiodarone  Antineoplastics  Gold salts  Iodine  Lithium  Radiopharmaceuticals  Retinoids Although majority of the drugs excreted into the breastmilk are at small amounts, due to inherent vulnerability of the infant, significant adverse effects may result from inappropriate choice of medication and ill-advised drug use during Read more…

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Clinical Pharmacy

Drug Safety Alert: Aspirin and NSAIDs Interaction

When given with other NSAIDs, aspirin competes on similar sites on COX thereby limiting its efficacy in preventing platelet aggregation, presumably attenuating its cardioprotective effect. Increased cardiovascular events may result in concomitant use of low-dose aspirin and NSAIDs (ibuprofen & naproxen), especially when concomitantly given in prolonged periods of time (>10 days). Possible management is to give aspirin at least 30 minutes before or Read more…

By admin, ago
Breastfeeding

Medications in Breastfeeding

It is recommended by most organizations worldwide to provide six months of exclusive breastfeeding for infants. However, in the Philippines, only 34% of Filipino children under six months old are being exclusively breastfed.   One of the reasons why mothers discontinue breastfeeding is medication intake. Although most medications pass through the Read more…

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Clinical Pharmacy

Drug Interaction: Spironolactone with Potassium Supplements

Drug to drug interactions (DDIs) are a frequent problem to healthcare providers as they may produce untoward effects to their patients. The risk of DDIs increases with increasing simultaneous drug use.  All DDIs are preventable medication-related issues, which when resolved may lead to improved patient care.  Spironolactone is a competitive antagonist of aldosterone. This mechanism occurs in the Read more…

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Did You Know?

A Review on Polycystic Ovary Syndrome (PCOS)

  Polycystic ovary syndrome, also called PCOS or Stein-Leventhal syndrome is a common endocrine disorder amongst women in the childbearing stage. According to National Institutes of Health, an estimate of 4-10% of women of reproductive age suffer from PCOS. It was first described in 1935 by Stein and Leventhal as a condition with Read more…

By admin, ago
Cosmetics

Drug Safety Alert: Products with Hydroquinone

Hydroquinone has been popularly used for decades as a bleaching agent for treating skin pigmentation, as well as freckles and age spots. However, on January 2001, the European Union (EU) banned the use of hydroquinone in cosmetics due to mid-term side effects such as leukomelanderma en confettu and exogenous ochronosis. Other health agencies including Health Read more…

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Clinical Pharmacy

Paracetamol Dose

  Paracetamol, the international nonproprietary name, is a commonly used antipyretic and analgesic. The usual recommended dose for adults is 500mg to 1g every 4 to 6 hours. Some regulatory agencies have capped the maximum daily dose in over-the-counter use up to 3000mg – 3250mg/day, but may still be given Read more…

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Did You Know?

2015 Global Adult Tobacco Survey

The Tobacco Regulation Act and the Consumers Act of the Philippines have regulated smoking by banning all tobacco advertisements and sponsorships, prohibiting smoking in public and sales to minors, and revising labelling and packaging of cigarettes. According to the Global Adult Tobacco Survey in 2015, the prevalence of tobacco smoking Read more…

By admin, ago
Clinical Pharmacy

Drug Safety Alert: Loperamide

  Loperamide is a weak opioid agonist and works by slowing the movement of intestines. It is an over-the-counter (OTC) medication used to control the symptoms of diarrhea, including Travelers’ diarrhea. The maximum daily dose for adults is 8mg for OTC use, while 16mg for prescription use. It is relatively safe with low gastrointestinal absorption and poor Read more…

By admin, ago